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ANEURYSM@RISK: automatic intracranial aneurysm quantification, 4D flow MRI...
We aim to improve rupture risk prediction by technical innovations 1) enabling automatic assessment of the UIA shape (including size), 2) determining the effect of the bloodflow... -
DETERMINANTS OF SUSCEPTIBILITY IN INHERITED CARDIOMYOPATHY: TOWARDS NOVEL...
Inherited cardiomyopathies (CM) are clinically heterogeneous: age of onset and disease-severity differ greatly between patients with the exact same gene mutation. The mechanisms... -
PREDICT2
To improve treatment of ventricular arrhythmias, research is conducted on many different levels: genetics, basic and clinical electrophysiology, national registries, human samples. -
GeranylGeranylAcetone in Heart failure with preserved ejection fraction
In this phase 2 trial, we expect to obtain proof of concept for a beneficial effect of GGA on HFpEF. In HFpEF patients we will evaluate effects of GGA on signs and symptoms of... -
DEFENCE: Determination and Evaluation of the Frequency and Effects of...
With our project we strive to maximally utilize existing data and registries. However, new data needs to be collected, primarily due to three reasons: (1) routine clinical care... -
Early detection of cardiac dysfunction in childhood cancer survivors; a LATER study
We collected cardiac data (history, phusica; examination, Echo, ECG, Blood) from 1550 chidlhood cancer survivors and 250 sibling. -
ArmCoach4Stroke
The multidisciplinary ArmCoach4Stroke project aims to develop and evaluate a new and interactive therapy aid based on movement sensors to stimulate and optimize the daily use... -
Circulating Nanotraces to Identify the Cause of Stroke
To develop a liquid biopsy biomarker that can differentiate between the cause of stroke (ischemic and hemorrhagic stroke) in the acute phase, new technology will be developed... -
CAPACITY-COVID
CAPACITY is a registry of patients with COVID-19 across Europe and has been established to answer questions on the role of cardiovascular disease in this pandemic. It is an... -
Digoxin Evaluation in Chronic heart failure: Investigational Study In...
Investigation whether low-level, aiming for serum concentrations 0.5-0.9ng/mL, digoxin on top of standard treatment (guideline-recommended therapy), is beneficial in HF patients... -
CAPACITY 2: A prospective cohort study evaluating the occurrence of short...
For this reason, there is an urgent need for large prospective cohort studies in which patients with laboratory confirmed COVID-19 unselectively undergo standardized and long-... -
RADAR: Earlier Recognition of Aortic Dissection and Aneurysm Rupture: The RADAR Study
Aortic aneurysm is a life-threatening condition. When undetected, an aneurysm can grow and evolve into dissection or rupture. This RADAR-consortium will develop methods to... -
Outflow tract related aging with congenital heart defects: identifying...
Retrospective cohort study in patients with atrial switch operation, longitudinal Follow Up -
QRS vectors in Solving the Inverse Problem of Electrocardiography
Electrocardiographic imaging in patients to identify early signs of disease in arrhytmogenic cardiomyopathy. Therefore, clinical MRI/CT, body surface mapping (64-electrode ECG)... -
Inflammatory Reprogramming by Ageing and Microbiome - Targets for Treatment...
IN-CONTROL II will seek to i. unravel the mechanisms driving 'trained immunity" in patients, taking into account the impact of senescence, age, gender and obesity, ii. elucidate... -
Colchicin in patients with chronic coronary disease
Double blind randomised clinical trial with colchicin/ placebo in patients with chronic coronary disease. 5552 Pts in Netherlands and Australia -
Recognizing sudden cardiac arrest vulnerability in diabetes
The RESCUED study investigates the risk of a sudden cardiac arrest in diabetes patients. The aim is to improve recognition of individuals at high risk of sudden cardiac arrest... -
Pulmonary Hypertension and AssociatED Right heart fAilure: IMproved outcomes...
PAH is a deadly disease characterized by abnormal remodelling of pulmonary vessels, leading to a progressive increase in pulmonary artery pressure and right heart failure.... -
Heart-Brain Connection & Heart-Brain Connection - crossroads
Cognitive impairment is common among people with cardiovascular or cerebrovascular disease. HBC1 explored the etiological role of hemodynamic factors in cognitive impairment,... -
Outflow tract related aging with congenital heart disease. Workpackage...
Rationale: Tetralogy of Fallot is the most common type of cyanotic congenital heart disease. The main problems of this patient population are heart failure related to chronic...
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