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The efficacy of aspirin to inhibit platelet aggregation in patients...
We investigated whether hyperaggregation occurs during infection, and whether aspirin inhibits this. Patients hospitalised due to acute infection were randomised to receive 10... -
GENIUS II
We have from the atheroexpress biobank (UMCU) cell isolates from atherectomy samples and blood cells -
Cardiac complications in Patients with SARS Corona virus 2 registry
The aim of CAPACITY is to collect data regarding the cardiovascular history, diagnostic information and occurrence of cardiovascular complications in COVID-19 patients. By... -
Deep neural networks for ECG interpretation and home cardiac monitoring
Development of deep neural networks for automated analysis of electrocardiograms (ECGs) and of a medical device to obtain a multi-lead device at home. Both innovations will be... -
PREDICT2
To improve treatment of ventricular arrhythmias, research is conducted on many different levels: genetics, basic and clinical electrophysiology, national registries, human samples. -
GeranylGeranylAcetone in Heart failure with preserved ejection fraction
In this phase 2 trial, we expect to obtain proof of concept for a beneficial effect of GGA on HFpEF. In HFpEF patients we will evaluate effects of GGA on signs and symptoms of... -
Self TRAcking for Prevention and diagnosis of heart disease
We investigate diagnostic technologies to reduce cardiovascular disease. We use questionnaires, serious gaming, electrocardiography, digital stethoscopes and other eHealth... -
DEFENCE: Determination and Evaluation of the Frequency and Effects of...
With our project we strive to maximally utilize existing data and registries. However, new data needs to be collected, primarily due to three reasons: (1) routine clinical care... -
MyDigiTwin: Using Big-Data to put a cardiovascular digital twin into the...
The MyDigiTwin consortium will build the MyDigiTwin platform on top of the Personal health record depositories (Dutch: Persoonlijke Gezondheidsomgeving; PGO), enabling users to... -
CAPACITY-COVID
CAPACITY is a registry of patients with COVID-19 across Europe and has been established to answer questions on the role of cardiovascular disease in this pandemic. It is an... -
Digoxin Evaluation in Chronic heart failure: Investigational Study In...
Investigation whether low-level, aiming for serum concentrations 0.5-0.9ng/mL, digoxin on top of standard treatment (guideline-recommended therapy), is beneficial in HF patients... -
CAPACITY 2: A prospective cohort study evaluating the occurrence of short...
For this reason, there is an urgent need for large prospective cohort studies in which patients with laboratory confirmed COVID-19 unselectively undergo standardized and long-... -
RADAR: Earlier Recognition of Aortic Dissection and Aneurysm Rupture: The RADAR Study
Aortic aneurysm is a life-threatening condition. When undetected, an aneurysm can grow and evolve into dissection or rupture. This RADAR-consortium will develop methods to... -
Early detection of 'silent' myocardial ischemia and cardiac dysfunction in...
Population-based study investigating the diagnostic yield of stress perfusion MRI for early detection of coronary heart disease in asymptomatic individuals with increased... -
Determination and Evaluation of the Frequency and Effects of myocardial...
Within DEFENCE, all large national COVID-19 studies aimed at unravelling the relationship between cardiovascular disease and COVID-19 are brought together. The main aim of... -
Improving prevention of cardiovascular disease: from proof of principle to...
Using big data analytics to develop flexible and improved cardiovascular risk prediction algorithms integrated and 'live' in routine clinical practice in order to improve... -
Video monitoring FOR early Signaling of adverse EvEnts
This project explores continuous video monitoring of the cardiorespiratory status of a patient as an innovative unobtrusive method that could aid to reduce workload for the... -
Colchicin in patients with chronic coronary disease
Double blind randomised clinical trial with colchicin/ placebo in patients with chronic coronary disease. 5552 Pts in Netherlands and Australia -
Heart-Brain Connection & Heart-Brain Connection - crossroads
Cognitive impairment is common among people with cardiovascular or cerebrovascular disease. HBC1 explored the etiological role of hemodynamic factors in cognitive impairment,... -
EaRly diagnosis of Stable and Unstable Angina uSIng extracellular VEsicles
Extracellular vesicle proteins in plasma subfractions are investigated to determine their ability for early diagnosis of stable and unstable angina using a blood test
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