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Race V - Poaf
primary aim: study molecular mechanisms of AF by combining histology, biochemical analysis, and genome-wide RNA expression profiles. Secondary aim: study the incidence of AF... -
DETECTIN-HF
Dilated cardiomyopathy is a major cause of heart failure and is the main indication of cardiac transplantation. About 30-50% of the cases can be explained by genetic... -
The efficacy of aspirin to inhibit platelet aggregation in patients...
We investigated whether hyperaggregation occurs during infection, and whether aspirin inhibits this. Patients hospitalised due to acute infection were randomised to receive 10... -
ENERGISE, Targeting energy metabolism to combat cardiovascular disease
this is not one project but a collection of cohort studies, human experimental words and much more -
Circulating Nanotraces to Identify the Cause of Stroke
To develop a liquid biopsy biomarker that can differentiate between the cause of stroke (ischemic and hemorrhagic stroke) in the acute phase, new technology will be developed... -
DETERMINANTS OF SUSCEPTIBILITY IN INHERITED CARDIOMYOPATHY: TOWARDS NOVEL...
Inherited cardiomyopathies (CM) are clinically heterogeneous: age of onset and disease-severity differ greatly between patients with the exact same gene mutation. The mechanisms... -
Detection Of Latent Pulmonary Hypertension In Genetically Susceptible Individuals
longitudinal follow-up program for unaffected mutation carriers at risk for developing pulmonary arterial hypertension -
CVON ARGUS
CCTA and adenosine CMR imaging of women and men with chest pain symptoms -
GeranylGeranylAcetone in Heart failure with preserved ejection fraction
In this phase 2 trial, we expect to obtain proof of concept for a beneficial effect of GGA on HFpEF. In HFpEF patients we will evaluate effects of GGA on signs and symptoms of... -
Colchicin in patients with chronic coronary disease
Double blind randomised clinical trial with colchicin/ placebo in patients with chronic coronary disease. 5552 Pts in Netherlands and Australia -
Atrial Fibrillation Fingerprinting
Atrial fibrillation (AF) is the most common age-related cardiac rhythm disorder accounting for about one-third of rhythm abnormalities related hospitalizations with annual costs... -
Detection Of Latent Pulmonary Hypertension In Genetically Susceptible Individuals
longitudinal follow-up program for early detection of PAH in unaffected carriers. these carriers are compared with Idiopathic PAH patients, heritable PAH patients and healthy... -
IMPRESS
This project aims at investigating if the mechanism of trained immunity plays a role in the development of atherosclerosis in women with former preeclampsia. -
GeranylGeranylAcetone in Heart failure with preserved ejection fraction
In this phase 2 trial, we expect to obtain proof of concept for a beneficial effect of GGA on HFpEF. In HFpEF patients we will evaluate effects of GGA on signs and symptoms of...
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