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Race V - Poaf
primary aim: study molecular mechanisms of AF by combining histology, biochemical analysis, and genome-wide RNA expression profiles. Secondary aim: study the incidence of AF... -
ENERGISE, Targeting energy metabolism to combat cardiovascular disease
this is not one project but a collection of cohort studies, human experimental words and much more -
Pulmonary Hypertension and AssociatED Right heart fAilure: IMproved outcomes...
PAH is a deadly disease characterized by abnormal remodelling of pulmonary vessels, leading to a progressive increase in pulmonary artery pressure and right heart failure.... -
DETERMINANTS OF SUSCEPTIBILITY IN INHERITED CARDIOMYOPATHY: TOWARDS NOVEL...
Inherited cardiomyopathies (CM) are clinically heterogeneous: age of onset and disease-severity differ greatly between patients with the exact same gene mutation. The mechanisms... -
GENIUS II
We have from the atheroexpress biobank (UMCU) cell isolates from atherectomy samples and blood cells -
Technology Of Protein delivery through Extracellular Vesicles to target PCSK9
High total cholesterol levels are a major cause of disease burden in both the developed and developing world as a risk factor for ischemic heart disease and stroke. Lowering... -
Inflammatory Reprogramming by Ageing and Microbiome - Targets for Treatment...
IN-CONTROL II will seek to i. unravel the mechanisms driving 'trained immunity" in patients, taking into account the impact of senescence, age, gender and obesity, ii. elucidate... -
Atrial Fibrillation Fingerprinting
Atrial fibrillation (AF) is the most common age-related cardiac rhythm disorder accounting for about one-third of rhythm abnormalities related hospitalizations with annual costs... -
PREDICT2
To improve treatment of ventricular arrhythmias, research is conducted on many different levels: genetics, basic and clinical electrophysiology, national registries, human samples. -
IMPRESS
This project aims at investigating if the mechanism of trained immunity plays a role in the development of atherosclerosis in women with former preeclampsia.
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