@prefix adms: <http://www.w3.org/ns/adms#> .
@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix dcatap: <http://data.europa.eu/r5r/> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix healthdcatap: <http://healthdataportal.eu/ns/health#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix vcard: <http://www.w3.org/2006/vcard/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://fdp.heart-institute.nl/dataset/5b7df7f3-2b6d-4b7b-88a9-9246e013701f> a dcat:Dataset ;
    dcatap:applicableLegislation <http://data.europa.eu/eli/reg/2025/327/oj> ;
    healthdcatap:maxTypicalAge "43"^^xsd:nonNegativeInteger ;
    healthdcatap:minTypicalAge "12"^^xsd:nonNegativeInteger ;
    healthdcatap:numberOfUniqueIndividuals "30"^^xsd:nonNegativeInteger ;
    healthdcatap:populationCoverage "collection type: Case-Control,Disease specific,Longitudinal,Population-based | data categories: Imaging data,Medical records,Physiological/Biochemical measurements,Survey data | materials: Serum | omics: Not available | imaging: Y | sex: Female,Male"@nl ;
    dct:accessRights <http://publications.europa.eu/resource/authority/access-right/RESTRICTED> ;
    dct:creator [ a foaf:Agent ;
            dct:identifier "DCVA" ;
            vcard:hasEmail <mailto:info@dcvalliance.nl> ;
            foaf:homepage <https://www.dcvalliance.nl/> ;
            foaf:name "Dutch Cardiovascular Alliance (DCVA)" ] ;
    dct:description ""@en,
        "Rationale: Tetralogy of Fallot is the most common type of cyanotic congenital heart disease. The main problems of this patient population are heart failure related to chronic pulmonary regurgitation, arrhythmias and sudden cardiac death. A major gap in our knowledge is how coupling between the RV and pulmonary artery affects outcomes. It has been shown that aortic pulse wave velocity can be improved by exercise training in Tetralogy of Fallot.  Objective: Primary Objective: To examine the effect of an online based exercise training protocol on ventriculo-arterial coupling , as assessed by pulse wave velocity in the aorta and pulmonary artery in patients operated for  Tetralogy of Fallot.  Study design:  cross-over interventional study. All children and young adults will be randomized in 2 groups. One group will start with care/exercise as usual, the other group will start with an online exercise training. After 12 weeks the groups will change from protocol. Before start of measurements, after 12 weeks and group 2 after 24 weeks, all participants will undergo a number of tests, including echocardiogram, cardiopulmonary exercise test, and cardiac magnetic resonance imaging.   Study population: 12-30 years of age, after surgical repair of tetralogy of Fallot (TOF), being followed at one of the 2 locations of the Academic Center for Congenital Heart disease (ACAHA).  Intervention: 12 weeks of online based interval training 3 times a week.  Main study parameters/endpoints: Decrease in pulse wave velocity in the aorta and pulmonary artery measured by MRI."@nl ;
    dct:identifier "DCVA-063" ;
    dct:issued "2020-01-01T00:00:00+00:00"^^xsd:dateTime ;
    dct:language <http://id.loc.gov/vocabulary/iso639-1/en> ;
    dct:modified "2026-05-13T11:47:36.201864"^^xsd:dateTime ;
    dct:provenance [ a dct:ProvenanceStatement ;
            rdfs:label ""@en,
                ""@nl ] ;
    dct:publisher [ a foaf:Agent ;
            dct:identifier "DCVA" ;
            vcard:hasEmail <mailto:info@dcvalliance.nl> ;
            foaf:homepage <https://www.dcvalliance.nl/> ;
            foaf:name "Dutch Cardiovascular Alliance (DCVA)" ] ;
    dct:spatial <http://publications.europa.eu/resource/authority/country/NLD> ;
    dct:temporal [ a dct:PeriodOfTime ;
            dcat:endDate "2025-12-31T00:00:00+00:00"^^xsd:dateTime ;
            dcat:startDate "2020-01-01T00:00:00+00:00"^^xsd:dateTime ] ;
    dct:title ""@en,
        "Outflow tract related aging with congenital heart disease. Workpackage Tetraogy of fallot High Intensity Interval Training"@nl ;
    adms:versionNotes ""@en,
        ""@nl ;
    dcat:contactPoint [ a vcard:Kind ;
            vcard:fn "DCVA" ;
            vcard:hasEmail <mailto:info@dcvalliance.nl> ;
            vcard:hasURL <['https://www.dcvalliance.nl/']> ] ;
    dcat:keyword "Case-Control"@nl,
        "Disease specific"@nl,
        "Female"@nl,
        "Imaging data"@nl,
        "Longitudinal"@nl,
        "Male"@nl,
        "Medical records"@nl,
        "Not available"@nl,
        "OUTREACH  ToFHIIT study"@nl,
        "Physiological Biochemical measurements"@nl,
        "Population-based"@nl,
        "Serum"@nl,
        "Survey data"@nl ;
    dcat:qualifiedAttribution [ a dcat:Attribution ;
            dcat:agent [ a foaf:Agent,
                        foaf:Organization ;
                    dct:identifier "DCVA" ;
                    foaf:homepage <https://www.dcvalliance.nl/> ;
                    foaf:mbox <mailto:info@dcvalliance.nl> ;
                    foaf:name "Dutch Cardiovascular Alliance (DCVA)" ] ] ;
    dcat:theme <http://publications.europa.eu/resource/authority/data-theme/HEAL> .

<http://data.europa.eu/eli/reg/2025/327/oj> a <http://data.europa.eu/eli/ontology#LegalResource> .

<http://id.loc.gov/vocabulary/iso639-1/en> a dct:LinguisticSystem .

<http://publications.europa.eu/resource/authority/access-right/RESTRICTED> a dct:RightsStatement .

<http://publications.europa.eu/resource/authority/country/NLD> a dct:Location .