61 datasets gevonden

Follow up of women (with obesity and unfulfilled wish for a child) and their children who participated in a preconception lifestyle intervention with focus on women's lifestyle,...

Rationale: Tetralogy of Fallot is the most common type of cyanotic congenital heart disease. The main problems of this patient population are heart failure related to chronic...

The bicuspid aortic valve is generally considered to be a result of a congenital fusion of two out of three leaflets. We found that the non-coronary leaflet develops from the...

This project is focused on developing new MRI hardware and software for improved phenotyping of patients with HFpEF

large small molecule screen to identify compounds that enhance 5-oxoprolinase activity.

We aim to improve rupture risk prediction by technical innovations 1) enabling automatic assessment of the UIA shape (including size), 2) determining the effect of the bloodflow...

multicenter, prospective randomised controlled trial to evaluate the efficacy of a watchful waiting strategy (rate control for symptom relief) compared to routine care...

In CREW we addressed the following topics: - The prevalence of (subclinical) CVD in middle-aged women with PCOS/POI - The prevalence of (subclinical) CVD in middle-aged women...

primary aim: study molecular mechanisms of AF by combining histology, biochemical analysis, and genome-wide RNA expression profiles. Secondary aim: study the incidence of AF...

We propose a new treatment methodology that 1) is able to predict an upcoming ventricular tachy-arrhythmic event and 2) can initiate a preventive intervention. This methodology...

ERASE will deliver: 1. Knowledge if we should also offer screening for intracranial aneurysms (IA) to persons 1. who have a positive family history with first degree relatives...

With our project we strive to maximally utilize existing data and registries. However, new data needs to be collected, primarily due to three reasons: (1) routine clinical care...

CAPACITY is a registry of patients with COVID-19 across Europe and has been established to answer questions on the role of cardiovascular disease in this pandemic. It is an...

A campaign to inform the general public and online tools to evaluate indications for cardiogenetic referral will be launched. The yield of novel methods to reach out to family...

BENEFIT is an ecosystem for healthy living and an integrated loyalty program that rewards patients for the time and energy spent on healthy lifestyle activities. By rewarding...

Dilated cardiomyopathy is a major cause of heart failure and is the main indication of cardiac transplantation. About 30-50% of the cases can be explained by genetic...

To invetigate if Low-dose Digoxin can effectively reduce cardiovascular mortality and recurrent HF hospitalizations, on top of the guideline-recommended therapies in HF patients...

To optimally use brain imaging data in vascular cognitive impairment (VCI), the ImProVas project (i) develops and validates methods for automatic quantification of microbleeds...

Aortic aneurysm is a life-threatening condition. When undetected, an aneurysm can grow and evolve into dissection or rupture. This RADAR-consortium will develop methods to...

In the five year LIKE programme (2017-2022), we develop, implement and evaluate an integrated action programme at the level of family, school, neighbourhood, health care and...