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EaRly diagnosis of Stable and Unstable Angina uSIng extracellular VEsicles
Extracellular vesicle proteins in plasma subfractions are investigated to determine their ability for early diagnosis of stable and unstable angina using a blood test -
Pulmonary Hypertension and AssociatED Right heart fAilure: IMproved outcomes...
PAH is a deadly disease characterized by abnormal remodelling of pulmonary vessels, leading to a progressive increase in pulmonary artery pressure and right heart failure.... -
Determination and Evaluation of the Frequency and Effects of myocardial...
Within DEFENCE, all large national COVID-19 studies aimed at unravelling the relationship between cardiovascular disease and COVID-19 are brought together. The main aim of... -
DETERMINANTS OF SUSCEPTIBILITY IN INHERITED CARDIOMYOPATHY: TOWARDS NOVEL...
Inherited cardiomyopathies (CM) are clinically heterogeneous: age of onset and disease-severity differ greatly between patients with the exact same gene mutation. The mechanisms... -
Detection Of Latent Pulmonary Hypertension In Genetically Susceptible Individuals
longitudinal follow-up program for unaffected mutation carriers at risk for developing pulmonary arterial hypertension -
Self TRAcking for Prevention and diagnosis of heart disease
We investigate diagnostic technologies to reduce cardiovascular disease. We use questionnaires, serious gaming, electrocardiography, digital stethoscopes and other eHealth... -
CVON ARGUS
CCTA and adenosine CMR imaging of women and men with chest pain symptoms -
MyDigiTwin: Using Big-Data to put a cardiovascular digital twin into the...
The MyDigiTwin consortium will build the MyDigiTwin platform on top of the Personal health record depositories (Dutch: Persoonlijke Gezondheidsomgeving; PGO), enabling users to... -
GeranylGeranylAcetone in Heart failure with preserved ejection fraction
In this phase 2 trial, we expect to obtain proof of concept for a beneficial effect of GGA on HFpEF. In HFpEF patients we will evaluate effects of GGA on signs and symptoms of... -
GENIUS II
We have from the atheroexpress biobank (UMCU) cell isolates from atherectomy samples and blood cells -
Early detection of cardiac dysfunction in childhood cancer survivors; a LATER study
We collected cardiac data (history, phusica; examination, Echo, ECG, Blood) from 1550 chidlhood cancer survivors and 250 sibling. -
Automatic CTA Image Analysis to Support Treatment Selection in Acute Stroke
Proper treatment selection in the acute phase of ischemic stroke can considerably improve patient outcome, as shown by recent studies. In the setting of acute stroke, treatment... -
BRAIN@Risk
Functional and structural MRI biomarkers of large and small vessel disease of the cerebral vasculature. -
Colchicin in patients with chronic coronary disease
Double blind randomised clinical trial with colchicin/ placebo in patients with chronic coronary disease. 5552 Pts in Netherlands and Australia -
CAPACITY 2: A prospective cohort study evaluating the occurrence of short...
For this reason, there is an urgent need for large prospective cohort studies in which patients with laboratory confirmed COVID-19 unselectively undergo standardized and long-... -
Inflammatory Reprogramming by Ageing and Microbiome - Targets for Treatment...
IN-CONTROL II will seek to i. unravel the mechanisms driving 'trained immunity" in patients, taking into account the impact of senescence, age, gender and obesity, ii. elucidate... -
Atrial Fibrillation Fingerprinting
Atrial fibrillation (AF) is the most common age-related cardiac rhythm disorder accounting for about one-third of rhythm abnormalities related hospitalizations with annual costs... -
Detection Of Latent Pulmonary Hypertension In Genetically Susceptible Individuals
longitudinal follow-up program for early detection of PAH in unaffected carriers. these carriers are compared with Idiopathic PAH patients, heritable PAH patients and healthy... -
QRS vectors in Solving the Inverse Problem of Electrocardiography
Electrocardiographic imaging in patients to identify early signs of disease in arrhytmogenic cardiomyopathy. Therefore, clinical MRI/CT, body surface mapping (64-electrode ECG)...
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