Outflow tract related aging with congenital heart defects: identifying causes and mechanisms of myocardial and large vessel wall adaptation, predictors for long term outcome and targets for improved treatment.

The CAS study is a clinical observational study investigating the effects of ConAoS on the left ventricular function and the prevalence, pattern and expanse of LVH, myocardial stiffness and myocardial fibrosis. Moreover, we will assess the prognostic capacity of the presence of these pathological processes, correlating our findings at baseline to clinical outcome by assessing the occurrence of cardiovascular events and all-cause mortality during 3-year clinical follow-up. We will unravel biomarker and imaging predictors for myocardial dysfunction (systolic and diastolic) with specific attention for male-female differences

1. http://publications.europa.eu/resource/authority/data-theme/HEAL

1. http://id.loc.gov/vocabulary/iso639-1/en

1. http://data.europa.eu/eli/reg/2025/327/oj

collection type: Cohort,Disease specific,Image collection | data categories: Imaging data,Medical records | materials: Not available | omics: Not available | imaging: Y | sex: Female,Male,Undifferentiated