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The Gut Microbiome of liver transplant recipients – Cross-sectional +...
TransplantLines is designed as a single-center, prospective cohort study and biobank including all different types of solid organ transplant recipients as well as living organ... -
Single-cell dissection of the immune response after a myocardial infarction
The immune response plays a pivotal role in initiating cardiac repair and remodeling in both the acute and chronic phase after ST-Elevated myocardial infarction (STEMI). To... -
DNA methylation in bronchial biopsies of asthmatics, asthma in remission and...
The study focus was differential methylation in bronchial biopsies between persistent asthma, asthma in remission and healthy controls using Illumina 450k arrays. -
Gluten-free microbiome study UMCG
Gluten-free diet intervention: 11 individuals, 3 time points (T1: 1 week before intervention, T2: at the intervention; T3: 5 weeks after intervention. Fecal samples taken at... -
AcuteLines
Research in acute care faces many challenges, including enrollment challenges, legal limitations in data sharing, limited funding, and lack of singular ownership of the domain... -
CS Baby Biome
CS Baby Biome randomized control trial aims to investigate if the timing of intrapartum antibiotics given to mother influences the infant gut microbiome composition. The study... -
RSV infection of primary bronchial epithelial cells in asthma
Primary bronchial epithelial cells derived from healthy donors and asthma patients were differentiated in Air-Liquid-Interface condition and infected with the respiratory... -
Gene expression by RNAseq in bronchial biopsies of asthmatics, asthma in...
The study focus was differential expression in bronchial biopsies between persistent asthma, asthma in remission and healthy controls using RNAseq. -
Neoadjuvant immune checkpoint blockade in women with mismatch repair...
Neoadjuvant immune checkpoint blockade (ICB) has shown unprecedented activity in mismatch repair deficient (MMRd) colorectal cancers, but its effectiveness in MMRd endometrial... -
Lifelines NEXT
Lifelines NEXT (LLNEXT) is a birth cohort designed to study the effects of intrinsic and extrinsic determinants on health and disease as epidemiological research has shown there... -
Academisch Huisarts Ontwikkel Netwerk
The Academic General Practitioner Network (AHON), part of the Department of Primary and Long-term Care of the University Medical Center Groningen (UMCG), manages the AHON-... -
Epigenome-wide association study of asthma remission in whole blood and...
Asthma is a chronic respiratory disease which is not curable, yet some patients experience spontaneous remission.In this study, we hypothesized that epigenetic mechanisms may be... -
Celiac disease meta-analysis
Celiac disease (CeD) is a common immune-mediated disease of the small intestine that is triggered by exposure to dietary gluten. While the HLA locus plays a major role in... -
Single cell whole genome sequencing of high hyperdiploid acute lymphoblastic leukemia
This dataset was collected from viable bone marrow cells obtained at diagnosis from nine patients with high hyperdiploid ALL and one normal bone marrow sample. All samples were... -
MeDALL epigenetics study
MeDALL- (Mechanisms of the Development of ALLergy) is a collaborative project supported by the European Union under the Health Cooperation Work Programme of the 7th Framework... -
Nasal brushes analysis
scRNA-seq samples from healthy and asthma donors part 1. -
Genome of the Netherlands
The Genome of the Netherlands (GoNL) Project characterizes DNA sequence variation, common and rare, for SNVs, short insertions and deletions (indels) and larger deletions in 769... -
Single-cell RNA sequencing dissects gene-environment interactions on gene...
This study aims to dissect gene-environment interactions on gene expression and regulation in immune cells using scRNA-seq data from 120 donors being stimulated with 3... -
PhIP-Seq LLD
Bacteriophage Immunoprecipitation Sequencing (PhIP-Seq) of LLD participants. Libraries and protocol were developed in the Weizmann Institute of Science. Two different libraries... -
Oncology Life Study
We have established a hospital-based data-biobank, entitled OncoLifeS (Oncological Life Study: Living well as a cancer survivor) to link routinely collected clinical data with...
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