Celiac disease meta-analysis

Celiac disease (CeD) is a common immune-mediated disease of the small intestine that is triggered by exposure to dietary gluten. While the HLA locus plays a major role in disease susceptibility, 39 non-HLA loci were also identified in a study of 24,269 individuals. We now build on this earlier study by adding 4,125 additional Caucasian samples including an Argentinian cohort genotyped on the Immunochip. In doing so, we not only confirm the previous associations, we also identify two novel independent genome-wide significant associations.

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Titel Celiac disease meta-analysis
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Celiac disease (CeD) is a common immune-mediated disease of the small intestine that is triggered by exposure to dietary gluten. While the HLA locus plays a major role in disease susceptibility, 39 non-HLA loci were also identified in a study of 24,269 individuals. We now build on this earlier study by adding 4,125 additional Caucasian samples including an Argentinian cohort genotyped on the Immunochip. In doing so, we not only confirm the previous associations, we also identify two novel independent genome-wide significant associations.
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http://umcgresearchdatacatalogue.nl/catalogue_rdf/api/rdf/Contacts/firstName=Iris&lastName=Jonker&resource=EGAS00001003805
Naam
Iris Jonker
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i.h.jonkers@umcg.nl
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    Publisher 1
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    http://umcgresearchdatacatalogue.nl/catalogue_rdf/api/rdf/Agents/id=UMCG&resource=EGAS00001003805
    Naam
    University Medical Center Groningen
    Name (translations)
    Email
    researchdatacatalogue@umcg.nl
    URL
    https://www.umcg.nl/
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    Publisher note
    Publisher type
    Identifier
    https://ror.org/03cv38k47
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    Creator 1
    URI
    http://umcgresearchdatacatalogue.nl/catalogue_rdf/api/rdf/Agents/id=UMCG&resource=EGAS00001003805
    Naam
    University Medical Center Groningen
    Name (translations)
    Email
    researchdatacatalogue@umcg.nl
    URL
    https://www.umcg.nl/
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    Publisher note
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    https://ror.org/03cv38k47
    Landing page https://ega-archive.org/studies/EGAS00001003805
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      Identifier https://metadata.ega-archive.org/studies/EGAS00001003805
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      Spatial resolution in meters
      Access rights http://publications.europa.eu/resource/authority/access-right/NON_PUBLIC
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      1. http://publications.europa.eu/resource/authority/data-theme/HEAL
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      1. http://data.europa.eu/eli/reg/2022/868/oj
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      Minimum typical age
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      Number of records
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      URI http://umcgresearchdatacatalogue.nl/catalogue_rdf/api/rdf/Resources/id=EGAS00001003805