Genome of the Netherlands

The Genome of the Netherlands (GoNL) Project characterizes DNA sequence variation, common and rare, for SNVs, short insertions and deletions (indels) and larger deletions in 769 individuals of Dutch ancestry selected from five biobanks under the auspices of the Dutch hub of the Biobanking and Biomolecular Research Infrastructure (BBMRI-NL). The samples come from a representative sample of 250 trio-families from all provinces in the Netherlands. The parent-offspring trios include adult individuals ranging in age from 19 to 87 years (mean=53 years; SD=16 years) from birth cohorts 1910-1994. Sequencing was done on blood-derived DNA from uncultured cells and accomplished coverage was 14-15x. Samples where contributed by LifeLines (http://lifelines.nl/lifelines-research/general), The Leiden Longevity Study (http://www.healthy-ageing.nl; http://www.langleven.net), The Netherlands Twin Registry (NTR: http://www.tweelingenregister. org), The Rotterdam studies, (http://www.erasmus-epidemiology.nl/rotterdamstudy) and the Genetic Research in Isolated Populations program (http://www.epib.nl/research/geneticepi/research.html#gip). The sequencing was carried out in collaboration with the Beijing Institute for Genomics (BGI). The analysis was done by a consortium lead by UMCG, LUMC, Erasmus MC, VU university and UMCU, see http://www.nlgenome.nl. Funding for the project was provided by the Netherlands Organization for Scientific Research under award number 184021007, dated July 9, 2009 and made available as a Rainbow Project of the Biobanking and Biomolecular Research Infrastructure Netherlands (BBMRI-NL).

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Titel Genome of the Netherlands
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The Genome of the Netherlands (GoNL) Project characterizes DNA sequence variation, common and rare, for SNVs, short insertions and deletions (indels) and larger deletions in 769 individuals of Dutch ancestry selected from five biobanks under the auspices of the Dutch hub of the Biobanking and Biomolecular Research Infrastructure (BBMRI-NL). The samples come from a representative sample of 250 trio-families from all provinces in the Netherlands. The parent-offspring trios include adult individuals ranging in age from 19 to 87 years (mean=53 years; SD=16 years) from birth cohorts 1910-1994. Sequencing was done on blood-derived DNA from uncultured cells and accomplished coverage was 14-15x. Samples where contributed by LifeLines (http://lifelines.nl/lifelines-research/general), The Leiden Longevity Study (http://www.healthy-ageing.nl; http://www.langleven.net), The Netherlands Twin Registry (NTR: http://www.tweelingenregister. org), The Rotterdam studies, (http://www.erasmus-epidemiology.nl/rotterdamstudy) and the Genetic Research in Isolated Populations program (http://www.epib.nl/research/geneticepi/research.html#gip). The sequencing was carried out in collaboration with the Beijing Institute for Genomics (BGI). The analysis was done by a consortium lead by UMCG, LUMC, Erasmus MC, VU university and UMCU, see http://www.nlgenome.nl. Funding for the project was provided by the Netherlands Organization for Scientific Research under award number 184021007, dated July 9, 2009 and made available as a Rainbow Project of the Biobanking and Biomolecular Research Infrastructure Netherlands (BBMRI-NL).
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Contact point 1
URI
http://umcgresearchdatacatalogue.nl/catalogue_rdf/api/rdf/Contacts/firstName=Gert-Jan&lastName=van%20de%20Geijn&resource=EGAS00001000644
Naam
Gert-Jan van de Geijn
Name (translations)
Email
gonl@bbmri.nl
Identifier
URL
    Publisher
    Publisher 1
    URI
    http://umcgresearchdatacatalogue.nl/catalogue_rdf/api/rdf/Agents/id=UMCG&resource=EGAS00001000644
    Naam
    University Medical Center Groningen
    Name (translations)
    Email
    researchdatacatalogue@umcg.nl
    URL
    https://www.umcg.nl/
    Type
    Publisher note
    Publisher type
    Identifier
    https://ror.org/03cv38k47
    Creator
    Creator 1
    URI
    http://umcgresearchdatacatalogue.nl/catalogue_rdf/api/rdf/Agents/id=UMCG&resource=EGAS00001000644
    Naam
    University Medical Center Groningen
    Name (translations)
    Email
    researchdatacatalogue@umcg.nl
    URL
    https://www.umcg.nl/
    Type
    Publisher note
    Publisher type
    Identifier
    https://ror.org/03cv38k47
    Landing page https://ega-archive.org/studies/EGAS00001000644
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    In Series
      Versie
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      Identifier https://metadata.ega-archive.org/studies/EGAS00001000644
      Frequency
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      Type
      Temporal coverage
      Temporal resolution
      Spatial coverage
      Spatial resolution in meters
      Access rights http://publications.europa.eu/resource/authority/access-right/NON_PUBLIC
      Other identifier
      Theme
      1. http://publications.europa.eu/resource/authority/data-theme/HEAL
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      Conforms to
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      Distribution
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      Analytics
      Applicable legislation
      1. http://data.europa.eu/eli/reg/2022/868/oj
      Has version
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      Purpose
      Health category
      Health theme
      Legal basis
      Minimum typical age
      Maximum typical age
      Number of records
      Number of records for unique individuals.
      Personal data
      Publisher note
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      Trusted Data Holder
      Population coverage
      Retention period
      Health data access body
      Qualified relation
      Provenance activity
      Qualified attribution
      Quality annotations
      URI http://umcgresearchdatacatalogue.nl/catalogue_rdf/api/rdf/Resources/id=EGAS00001000644