57 datasets gevonden

Investigation whether low-level, aiming for serum concentrations 0.5-0.9ng/mL, digoxin on top of standard treatment (guideline-recommended therapy), is beneficial in HF patients...

For this reason, there is an urgent need for large prospective cohort studies in which patients with laboratory confirmed COVID-19 unselectively undergo standardized and long-...

We propose a new treatment methodology that 1) is able to predict an upcoming ventricular tachy-arrhythmic event and 2) can initiate a preventive intervention. This methodology...

Rationale: Whilst patients with a tetralogy of Fallot have excellent survival in the present day, adverse events still occur regularly. However,risk stratification in these...

Aortic aneurysm is a life-threatening condition. When undetected, an aneurysm can grow and evolve into dissection or rupture. This RADAR-consortium will develop methods to...

Population-based study investigating the diagnostic yield of stress perfusion MRI for early detection of coronary heart disease in asymptomatic individuals with increased...

Within DEFENCE, all large national COVID-19 studies aimed at unravelling the relationship between cardiovascular disease and COVID-19 are brought together. The main aim of...

Using big data analytics to develop flexible and improved cardiovascular risk prediction algorithms integrated and 'live' in routine clinical practice in order to improve...

CONCRETE aims to evaluate whether GP access to CT calcium scoring leads to earlier CAD diagnosis and treatment. The design is a pragmatic cluster randomized trial in which...

Retrospective cohort study in patients with atrial switch operation, longitudinal Follow Up

Electrocardiographic imaging in patients to identify early signs of disease in arrhytmogenic cardiomyopathy. Therefore, clinical MRI/CT, body surface mapping (64-electrode ECG)...

DOMESTICO or the Dutch nOcturnal and hoME dialysis Study To Improve Clinical Outcomes is a nationwide, combined retrospective and prospective, observational cohort study that...

IN-CONTROL II will seek to i. unravel the mechanisms driving 'trained immunity" in patients, taking into account the impact of senescence, age, gender and obesity, ii. elucidate...

This project explores continuous video monitoring of the cardiorespiratory status of a patient as an innovative unobtrusive method that could aid to reduce workload for the...

Double blind randomised clinical trial with colchicin/ placebo in patients with chronic coronary disease. 5552 Pts in Netherlands and Australia

The RESCUED study investigates the risk of a sudden cardiac arrest in diabetes patients. The aim is to improve recognition of individuals at high risk of sudden cardiac arrest...

PAH is a deadly disease characterized by abnormal remodelling of pulmonary vessels, leading to a progressive increase in pulmonary artery pressure and right heart failure....

Developing AI for ECG interpretation

Cognitive impairment is common among people with cardiovascular or cerebrovascular disease. HBC1 explored the etiological role of hemodynamic factors in cognitive impairment,...

Rationale: Tetralogy of Fallot is the most common type of cyanotic congenital heart disease. The main problems of this patient population are heart failure related to chronic...