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The efficacy of aspirin to inhibit platelet aggregation in patients...
We investigated whether hyperaggregation occurs during infection, and whether aspirin inhibits this. Patients hospitalised due to acute infection were randomised to receive 10... -
DETERMINANTS OF SUSCEPTIBILITY IN INHERITED CARDIOMYOPATHY: TOWARDS NOVEL...
Inherited cardiomyopathies (CM) are clinically heterogeneous: age of onset and disease-severity differ greatly between patients with the exact same gene mutation. The mechanisms... -
Deep neural networks for ECG interpretation and home cardiac monitoring
Development of deep neural networks for automated analysis of electrocardiograms (ECGs) and of a medical device to obtain a multi-lead device at home. Both innovations will be... -
GeranylGeranylAcetone in Heart failure with preserved ejection fraction
In this phase 2 trial, we expect to obtain proof of concept for a beneficial effect of GGA on HFpEF. In HFpEF patients we will evaluate effects of GGA on signs and symptoms of... -
WOMB project: Women Offspring and iMproving lifestyle for Better...
Follow up of women (with obesity and unfulfilled wish for a child) and their children who participated in a preconception lifestyle intervention with focus on women's lifestyle,... -
ArmCoach4Stroke
The multidisciplinary ArmCoach4Stroke project aims to develop and evaluate a new and interactive therapy aid based on movement sensors to stimulate and optimize the daily use... -
CAPACITY 2: A prospective cohort study evaluating the occurrence of short...
For this reason, there is an urgent need for large prospective cohort studies in which patients with laboratory confirmed COVID-19 unselectively undergo standardized and long-... -
RADAR: Earlier Recognition of Aortic Dissection and Aneurysm Rupture: The RADAR Study
Aortic aneurysm is a life-threatening condition. When undetected, an aneurysm can grow and evolve into dissection or rupture. This RADAR-consortium will develop methods to... -
Determination and Evaluation of the Frequency and Effects of myocardial...
Within DEFENCE, all large national COVID-19 studies aimed at unravelling the relationship between cardiovascular disease and COVID-19 are brought together. The main aim of... -
Improving prevention of cardiovascular disease: from proof of principle to...
Using big data analytics to develop flexible and improved cardiovascular risk prediction algorithms integrated and 'live' in routine clinical practice in order to improve... -
Outflow tract related aging with congenital heart defects: identifying...
Retrospective cohort study in patients with atrial switch operation, longitudinal Follow Up -
DOMESTICO prospectief
DOMESTICO or the Dutch nOcturnal and hoME dialysis Study To Improve Clinical Outcomes is a nationwide, combined retrospective and prospective, observational cohort study that... -
Heart-Brain Connection & Heart-Brain Connection - crossroads
Cognitive impairment is common among people with cardiovascular or cerebrovascular disease. HBC1 explored the etiological role of hemodynamic factors in cognitive impairment,... -
Outflow tract related aging with congenital heart disease. Workpackage...
Rationale: Tetralogy of Fallot is the most common type of cyanotic congenital heart disease. The main problems of this patient population are heart failure related to chronic... -
Device-based rate versus rhythm control treatment in patients with...
multicenter, prospective randomised controlled trial to evaluate the efficacy of a watchful waiting strategy (rate control for symptom relief) compared to routine care... -
Race V - Poaf
primary aim: study molecular mechanisms of AF by combining histology, biochemical analysis, and genome-wide RNA expression profiles. Secondary aim: study the incidence of AF... -
REVIVING EARLY DIAGNOSIS OF CARDIOVASCULAR DISEASE
A diagnostic cluster randomized trial in patients participating in primary care disease management programs for COPD or type 2 diabetes. An early diagnosis strategy will be... -
BENEFIT for all: The Ecosystem for Healthy Living
BENEFIT is an ecosystem for healthy living and an integrated loyalty program that rewards patients for the time and energy spent on healthy lifestyle activities. By rewarding... -
Detection Of Latent Pulmonary Hypertension In Genetically Susceptible Individuals
longitudinal follow-up program for early detection of PAH in unaffected carriers. these carriers are compared with Idiopathic PAH patients, heritable PAH patients and healthy... -
UNRAVELLING AETIOLOGY AND RISK FACTORS IN PATIENTS WITH A BICUSPID AORTIC VALVES
The bicuspid aortic valve is generally considered to be a result of a congenital fusion of two out of three leaflets. We found that the non-coronary leaflet develops from the...
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